This book constitutes the refereed proceedings of the 16th International Conference on Cellular Automata for Research and Industry, Cellular Automata, ACRI 2024, held in Florence, Italy, in September 9-11, 2024.

The 20 full papers presented were carefully reviewed and selected from 33 submissions. They were organized in the following topical sections: theory, mathematical and physical models; computational aspects and applications; social and biological models.